MLMP: A Methylation-Associated lncRNA-mRNA Prognostic Signature for Endometrial Carcinoma

Background

Endometrial carcinoma (EC) is one of the most common gynecological malignancies. Aberrant DNA methylation (DNAm) is an important epigenetic alteration involved in cancer progression. Long non-coding RNAs (LncRNAs) play critical roles in gene regulation and pathological processes. However, the biological and prognostic significance of lncRNA-mRNA pairs associated with methylation remains unclear.