Endoscopy
Cold versus hot snare endoscopic mucosal resection for 10-19-mm nonpedunculated colorectal polyps: a multicenter randomized trial
Par Jiang Q, An X, Yan X et 16 autres.
Contenu en anglais
Résumé
Background
Evidence for cold snare endoscopic mucosal resection (CS-EMR) in 10-19-mm nonpedunculated colorectal polyps is scarce. We conducted a multicenter randomized controlled trial (RCT) to compare CS-EMR against hot snare EMR (HS-EMR) in this setting.
Methods
We enrolled patients with 10-19-mm nonpedunculated colorectal polyps from 15 centers. Eligible polyps were individually randomized (1:1) to CS-EMR or HS-EMR. The primary outcome was histologic complete resection, analyzed in modified intention-to-treat (mITT) and per-protocol (PP) populations (noninferiority margin -10%). Secondary outcomes included en bloc resection, intraprocedural and delayed adverse events, and resection time.