Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Preliminary evaluation of the efficacy and safety of telitacicept in children with IgA nephropathy
Par Chen J, Yu XX, Shi XS et 3 autres.
Contenu en anglais
Résumé
Objectives
To preliminarily assess the efficacy and safety of telitacicept in pediatric IgA nephropathy (IgAN).
Methods
Clinical data of 11 children with IgAN who received telitacicept in the Department of Pediatrics, Provincial Hospital Affiliated to Fuzhou University, from January 2024 to October 2025 were retrospectively collected. Parameters compared before and after treatment included 24-hour urinary protein, serum albumin, immunoglobulins (IgG, IgA, IgM), peripheral blood CD19+ cells, estimated glomerular filtration rate (eGFR), and glucocorticoid dosage. Adverse events were recorded.