Lean Mass Index Adjustment of eGFR Strengthens Associations with Cardiometabolic Risk Factors

Background/Objectives: Serum creatinine (SCr)-based estimates of glomerular filtration rate (eGFRSCr) are influenced by muscle mass. This study investigated whether normalizing SCr to dual-energy X-ray absorptiometry (DEXA)-derived lean mass index (LMI) alters associations with cardiometabolic phenotypes.

Methods