International journal of nanomedicine
Chinese Medicine Led As-Doped Carbon Dot Nanoformulation for Effective Against Acute Promyelocytic Leukemia in Xenograft Model
Door Ou Y, Gu X, Ding K en 5 anderen.
Inhoud in het Engels
Abstract
Purpose
Acute promyelocytic leukemia (APL) is effectively treated with arsenic trioxide (ATO) and all-trans retinoic acid (ATRA), but arsenic-associated systemic toxicity remains an important clinical concern. This study aimed to develop a traditional Chinese medicine-inspired arsenic-doped carbon dot nanoplatform for APL therapy.