Clinical and genetic characteristics of patients with early-onset or familial parkinsonism: A retrospective single-center cohort

Background

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder after Alzheimer's disease. Hereditary causes account for 10-15% of cases but present considerably more complex clinical manifestations than idiopathic cases. It is therefore imperative to enhance clinicians' recognition of hereditary forms.