Association of Dysphagia and Oral Involvement with Growth and Nutritional Status in Pediatric Lipoid Proteinosis: A Prospective Cross-Sectional Study

Background/objectives

Lipoid proteinosis (LP) is a rare autosomal recessive genodermatosis characterized by oral and lingual involvement, frequently accompanied by dysphagia and recurrent oral ulcers. The relationships between these clinical manifestations and nutritional status or growth have not been clearly established. This study evaluated nutritional, growth, and micronutrient statuses in pediatric patients with LP and investigated their associations with dysphagia, oral ulcer frequency, and a composite oral involvement score.