Myricetin Modulates Quorum Sensing-Associated Phenotypes, Virulence, and Biofilm Formation in Pathogenic Bacteria: In Vitro and In Silico Studies

Background/Objectives: The rapid emergence of antimicrobial resistance (AMR) among pathogenic bacteria has necessitated the development of alternative therapeutic strategies that target bacterial virulence rather than cell viability.

Methods

In this study, the flavonoid myricetin was systematically evaluated for its antibacterial, QS-associated phenotypic and biofilm formation-inhibitory activities against clinically relevant bacterial pathogens.