Primary Pyogenic Ventriculitis in Adults: A Retrospective Case Series of Clinical Characteristics, Cerebrospinal Fluid Parameters, and Surgical Drain Managements

Background/Objectives: Primary pyogenic ventriculitis in adults is a rare, life-threatening central nervous system infection occurring in the absence of prior neurosurgical interventions or indwelling medical devices. Due to its scarcity, individual clinical trajectories, cerebrospinal fluid (CSF) cytochemical variations, and external ventricular drain (EVD) management timing remain poorly defined.