Results
Among the 2 094 adolescents, 999 (47.7%) were boys and 1 095 (52.3%) were girls, with an age range of 15 to 17 years and a mean age of (15.52±0.56) years. NSSI differed significantly by gender and only-child status (both P<0.05). The resistant, onset, persistent, and remission groups comprised 1 162, 221, 434, and 277 participants, respectively. In Model 1, stress significantly predicted self-criticism (β=0.362, 95% CI 0.314 to 0.408, P<0.001), and self-criticism significantly predicted NSSI onset (β=0.075, 95% CI 0.035 to 0.119, P<0.001). In Model 2, stress significantly predicted self-criticism (β=0.367, 95% CI 0.304 to 0.429, P<0.001), and self-criticism significantly predicted NSSI remission (β=-0.108, 95% CI -0.158 to -0.065, P<0.001). The indirect effects were significant in both Model 1 (β=0.027, 95% CI 0.012 to 0.044, P<0.001) and Model 2 (β=-0.039, 95% CI -0.061 to -0.023, P<0.001). However, the direct effects differed between the 2 models. In Model 1, stress directly predicted NSSI onset (β=0.065, 95% CI 0.032 to 0.102, P<0.001), whereas in Model 2, the direct effect of stress was not significant (β=-0.018, 95% CI -0.061 to 0.032, P=0.229). A parallel mediation model incorporating multiple dimensions of stress further indicated that interpersonal stress, academic stress, and adjustment problems indirectly predicted a higher likelihood of NSSI onset and a lower likelihood of NSSI remission through self-criticism, whereas the indirect effects of loss-related stress and punishment-related stress were not significant.