Extraction and Identification of the Sea Cucumber Holothuria Parva, Secondary Metabolites and Investigation of Their Potential Anti-SARS-Cov-2 Activities Using Molecular Docking

Background

Sea cucumbers are a class of valuable marine invertebrates, recognized for their importance in food and traditional medicine across many Asian countries. Their extracts contain various bioactive compounds, including phenolic compounds and saponins, which are of interest in medicinal chemistry. On the other hand, Considering the challenge of the viral disease COVID-19 still exists, and up to this time, the main protease (MPro) and papain-like protease (PLPro) of SARS-CoV-2 are key targets for developing and introducing molecules that act as anti-SARS-CoV-2 replication agents, whether these molecules are derived from natural sources or synthesized.