Systematic Review and Meta-Analysis of Patients with Esophageal Cancer and Intramural Metastasis

Purpose

Intramural metastasis is defined as the metastatic spread from a primary tumor to the gastrointestinal tract through the intramural lymphatic system. Although several studies have demonstrated the negative impact of intramural metastasis on survival in esophageal cancer, no systematic review including a large number of patients has been conducted yet.