Creatine Supplementation in Crohn's Disease: Possible Therapeutic Trends in Symptoms and Muscle Tissue Integrity

Background/objectives

Creatine (Cr) supplementation may serve as a nutritional intervention, enhancing gut metabolism and preserving lean body mass, specifically fat-free mass, thereby improving functional capacity and quality of life in individuals with Crohn's disease (CD). This paper aims to explore the potential mechanisms through which Cr supplementation may influence CD patients and review the current literature on this topic.