Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in recurrent aphthous stomatitis patients with iron deficiency

Background/purpose

Our previous study found that 101 of 430 recurrent aphthous stomatitis (RAS) patients have iron deficiency (ID). This study assessed whether all RAS patients with ID (so-called ID/RAS patients) had iron deficiency anemia (IDA) and evaluated whether the ID/RAS patients had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than healthy control subjects.