Biolimus- versus sirolimus-eluting stents in percutaneous coronary intervention: a comprehensive systematic review and meta-analysis of randomised controlled trials

Background

Sirolimus-eluting stents (SES) are a benchmark in percutaneous coronary intervention (PCI), while biolimus-eluting stents (BES), which combine a more lipophilic analogue with a biodegradable polymer, may enhance healing and reduce thrombosis. Whether these BES features translate into improved survival and cardiac outcomes compared with SES remains uncertain.