Biological performance enhancement of Ni-free Zr-based bulk metallic glass for dental implants via nitrogen plasma immersion ion implantation

Background/purpose

Improving the biocompatibility of bulk metallic glass (BMG) alloys is critical for expanding their applications in biomedical fields, particularly in dental implants. This study systematically investigated the suitability of nitrogen plasma immersion ion implantation (NPIII)-treated Zr-based BMG alloy for next-generation dental implant applications, focusing on protein adsorption, platelet responses, and cell behavior.