Clinical factors associated with carbapenem resistance and in-hospital mortality in Klebsiella pneumoniae bloodstream infection: a 7-year retrospective cohort study

Background

Carbapenem-resistant Klebsiella pneumoniae bloodstream infection (CRKP BSI) is associated with substantial mortality and limited therapeutic options, yet institutional epidemiology and risk profiles vary. We evaluated antimicrobial susceptibility, non-blood-site detection, factors associated with carbapenem resistance, and in-hospital all-cause mortality among patients with K. pneumoniae BSI at a secondary-care hospital over seven years.