Shared Tissue-Level Molecular Signatures and Immunometabolic Associations in Nonalcoholic Steatohepatitis and Chronic Kidney Disease: Potential Endothelial Relevance

Purpose

NASH and CKD are closely associated epidemiologically and share metabolic, inflammatory, and fibrotic features. This study integrated bulk-tissue transcriptomic datasets from both diseases to investigate shared tissue-level molecular signatures and their potential endothelial and immunometabolic relevance.