Caregiver-reported oral health-related quality of life in children with Mowat-Wilson syndrome: a comparative study

Background

Mowat-Wilson syndrome (MWS) is a rare genetic disorder characterized by intellectual disability, distinctive craniofacial features, behavioral impairments, and congenital anomalies. Although oral and craniofacial abnormalities are frequently reported, their impact on oral health-related quality of life (OHRQoL) has not been investigated. This study aimed to evaluate OHRQoL in children with MWS and compare it with peers with autism spectrum disorder (ASD) and neurotypical controls. Secondary analyses explored caregiver functional limitations and dental care characteristics.