Antibacterial activity of imipenem-encapsulated chitosan/HPMCP nanoparticles against clinical Acinetobacter baumannii isolates

Background

Multidrug-resistant Acinetobacter baumannii is an important healthcare-associated pathogen, necessitating therapeutic strategies. This study evaluates the antibacterial efficacy of imipenem-encapsulated chitosan/hydroxypropyl methylcellulose phthalate (Imp-Chi) nanoparticles against clinical A. baumannii isolates.