Journal of the Endocrine Society
Hippo signaling-linked circulating microRNA networks are associated with cardiovascular disease in type 2 diabetes
Par Besharat ZM, Trocchianesi S, Grieco GE et 19 autres.
Contenu en anglais
Résumé
Context
Type 2 diabetes (T2D) markedly increases the risk of cardiovascular disease (CVD). Circulating microRNAs (miRNAs) are promising biomarkers for patient stratification and may provide mechanistic insight into dysregulated pathways in T2D-associated CVD.
Objective
This work aimed to identify circulating miRNA signatures in T2D patients with CVD (T2D-CVD) vs T2D patients without CVD using a novel network-based medicine approach.