Annals of surgical treatment and research
Comparative clinical and molecular profiling of papillary thyroid carcinomas with unilateral and bilateral lateral lymph node metastasis: a retrospective cohort study
Par Shin HI, Jung CK, Joo YH et 1 autres.
Contenu en anglais
Résumé
Purpose
Studies on pathological and genetic features related to lateral lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC) remain limited. This study aimed to elucidate these features.
Methods
A total of 135 patients with PTC who underwent total thyroidectomy with lateral neck dissection between 2000 and 2021 were retrospectively analyzed. Next-generation sequencing-based mutation panel analysis was conducted for 26 cases with unilateral or bilateral LNM.