Journal of inflammation research
Network Pharmacology and Experimental Evidence Indicate That Dihydrochelerythrine from Toddalia asiatica Ameliorates Pathological Features of Knee Osteoarthritis in Rats and Is Associated with PI3K/AKT Signaling
Par Liu Y, Zhang Y, Zha Q et 4 autres.
Contenu en anglais
Résumé
Background
Toddalia asiatica is used in Chinese patent medicines for knee osteoarthritis (KOA), but the active constituents and experimental basis remain incompletely defined. This study examined whether dihydrochelerythrine (DHCHE) ameliorates structural and molecular changes in experimental KOA.