In Silico Design and Immunogenicity Evaluation of a Multiepitope Vaccine Candidate Against Leishmania tropica in BALB/c Mice

Background

Cutaneous leishmaniasis caused by Leishmania tropica remains a major neglected parasitic disease with limited therapeutic options and frequent treatment failure, highlighting the urgent need for effective vaccine-based interventions. Multiepitope vaccine (MEV) strategies provide a rational and targeted approach to induce defined cellular and humoral immune responses against Leishmania infection.