Adverse childhood experiences and functional stability in the affective-to-psychotic spectrum: a longitudinal multistate analysis of employment and relationship outcomes

Background

Adverse childhood experiences (ACEs) exert transdiagnostic influences on disorders of the affective-to-psychotic spectrum which share genetic similarities. While ACEs are established risk factors for developing disorders across this spectrum, the impact of ACEs on functional outcomes in adulthood remains insufficiently understood. This study aims to investigate the impact of ACEs on functional outcomes such as relationship and employment stability.