Canadian respiratory journal
Serum Glycoprotein VI in Acute Pulmonary Embolism: Association With Radiological Thrombus Burden and Clinical Risk Indicators
Par İnan MM, Sayhan MB, Salt Ö et 3 autres.
Contenu en anglais
Résumé
Background
Pulmonary embolism (PE) is a life-threatening condition requiring rapid diagnosis and accurate risk stratification. Biomarkers reflecting thromboinflammatory processes may improve early clinical assessment. Glycoprotein VI (GPVI), a key receptor involved in platelet activation, has been implicated in thrombus formation; however, its clinical relevance in PE remains unclear.
Objective
To examine the association of serum GPVI with radiological thrombus burden and clinical risk indicators in acute PE, while retaining the original PE-versus-control comparison only as a secondary exploratory case-control discrimination analysis, not as a diagnostic-accuracy analysis.