Nurse-Led and Nurse-Involved Antimicrobial Stewardship in Hospitals and Primary Care: Protocol for a Mixed Methods Systematic Review and Meta-Analysis With Gulf Cooperation Council and Middle East and North Africa Subgroup Analysis

Background

Antimicrobial resistance poses a growing threat to patient safety worldwide. Nurses are central to antimicrobial management; however, their contribution to formal antimicrobial stewardship (AMS) programs remains poorly characterized. To our knowledge, no previous review has combined evidence on the effectiveness and implementation of nurse-led and nurse-involved AMS interventions, including Gulf Cooperation Council and Middle East and North Africa (GCC/MENA) subgroup analysis.