Structured exercise and insulin resistance in adolescents with overweight or obesity: a systematic review and meta-analysis of randomised trials — analysis archive (PROSPERO CRD420261475742)

Locked analytic record of a prospectively registered systematic review and meta-analysis (PROSPERO CRD420261475742) of randomised trials of structured exercise versus non-exercise or diet-matched comparators on HOMA-IR in adolescents with overweight or obesity. Contents: inputs frozen before the single analysis run (effect-source table, moderators, strict-age flags, RoB 2 verdicts); the run (R script, log, session information, SHA-256 manifest); locked outputs (RESULTS_LOCK, DIAGNOSTICS_LOCK); study characteristics, RoB 2 and GRADE tables; identifier crosswalk; post-lock quality-control record; figures. No analysis was rerun after the freeze. See README.md. Authors: C.-C. Blăjuț, M. Hăncianu, L. Manole, E.-L. Spoială, L.M. Trandafir ("Grigore T. Popa" University of Medicine and Pharmacy, Iași, Romania). Funding: Health Programme (PS) 2021–2027, project INNODOC-MED, SMIS 351058.