[68Ga]Ga-SSO120 PET/CT Imaging in Pediatric Patients with Neuroblastoma: Biodistribution and Whole-Body Radiation Dosimetry

The clinical standard for neuroblastoma detection is based on targeting the norepinephrine transporter with [123I]MIBG, which has several challenges. Imaging the somatostatin receptor (SSTR) is a strong alternative. In contrast to standard DOTATATE, SSTR antagonist imaging with [68Ga]Ga-satoreotide trizoxetan ([68Ga]-SSO120) can potentially improve lesion detection as it targets both active and inactive SSTRs. We present the biodistribution and radiation exposure results of [68Ga]Ga-SSO120 PET/CT imaging in pediatric patients with neuroblastoma.