Ishige foliacea Water Extract (KDC22-01) Attenuates Tau Hyperphosphorylation and Ameliorates Scopolamine-Induced Memory Impairment in Mice

Background/Objectives: Ishige foliacea is an edible brown alga containing bioactive polyphenols with reported neuroprotective properties. Although extracts of I. foliacea have previously been shown to ameliorate cognitive impairment, their effects on pathological tau phosphorylation remain poorly characterized. This study investigated the neuroprotective and cognition-modulating effects of KDC22-01, an aqueous extract of I. foliacea.