Journal of Clinical Medicine
Plethysmography as a Complementary Tool for Monitoring Response to CFTR Modulator Therapy in Children with Cystic Fibrosis: A Real-World Study
Par Magdalena Postek, Katarzyna Walicka‐Serzysko, Urszula Borawska-Kowalczyk et 5 autres.
Contenu en anglais
Résumé
Background
Sensitive tools for monitoring response to cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy remain needed in children with cystic fibrosis (CF). Plethysmography may provide complementary information to spirometry and multiple-breath nitrogen washout (MBNW).
Aim
To characterize longitudinal changes in plethysmographic parameters before and during CFTR modulator therapy in children and adolescents with CF, using spirometry and MBNW as complementary physiological assessments.