Corneal Biomechanical and Tomographic Signatures for Keratoconus

Objectives

This study aimed to identify tomographic and biomechanical biomarkers that differentiate mild/moderate from advanced/severe keratoconus (KCN) based on the ABCD classification. The secondary objective was to assess the diagnostic performance of previously reported biomarkers for distinguishing KCN from KCN-free controls and to compare classifications derived from cohort-specific and previously established cutoff values, evaluating their consistency and potential generalizability in the Romanian KCN population.