Maternal Biochemical Profiles in Hypertensive Disorders of Pregnancy: An Observational Study

Background/Objectives: Hypertensive disorders of pregnancy are major contributors to maternal and perinatal morbidity and mortality. This study compared routinely available biochemical and hematological parameters across normotensive pregnancies, pregnancy-induced hypertension (PIH), and preeclampsia (PE), and evaluated their associations with established hypertensive pregnancy status.

Methods

This hospital-based observational study included 200 pregnant women at 24–34 weeks of gestation: 59 with PE, 61 with PIH, and 80 normotensive controls. Group differences, logistic regression associations, and discriminatory performance were assessed. An exploratory multivariable analysis compared PE directly with PIH.