Development of Triamcinolone Acetonide-Loaded Nanoparticles for Inflammatory Knee Arthritis Treatment

Introduction

Intra-articular corticosteroid injections (IACIs) provide an alternative treatment for inflammatory arthritis. Nevertheless, IACIs are limited by adverse effects, including injection-related pain, corticosteroid-induced chondrocyte toxicity, and progressive cartilage degeneration following prolonged use.