European Journal of Prosthodontics and Restorative Dentistry
Par Abdulrahman Saleh Alharbi, Abdulaziz Saad Alquhaibi, Reemana Waleed Alsudais et 5 autres.
Contenu en anglais
Alopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss. Vitamin D has been suggested as a potential biomarker for disease severity.
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To evaluate the association between vitamin D deficiency and alopecia areata severity in adults through a systematic review.
A systematic review was conducted according to the PRISMA 2020 guidelines. Electronic databases were searched through March 2026. Four observational studies met the inclusion criteria and were included in the qualitative synthesis. Study quality was assessed using the Newcastle– Ottawa Scale (NOS).
The included studies reported a higher prevalence of vitamin D deficiency among patients with alopecia areata than healthy controls. Three studies demonstrated a significant inverse association between serum vitamin D levels and disease severity, while one study found no significant association.
Vitamin D deficiency appears to be associated with increased severity of alopecia areata and may serve as a useful biomarker. However, further high-quality prospective studies are needed to confirm these findings.
Publié dans European Journal of Prosthodontics and Restorative Dentistry. Le résumé est reproduit tel qu’il a été publié et reste l’œuvre de ses auteurs ; lisez l’article complet à la source.
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